Polymorphism of deletion in mitochondrial DNA region V among 26 Han Chinese

LUO Yong-jun; GAO Wen-xiang; GAO Yu-qi; CHEN Jian; TAN Xiao-ling; LIU Xin

您当前的位置：

首页 >

文章列表页 >

Polymorphism of deletion in mitochondrial DNA region V among 26 Han Chinese

更新时间：2025-01-15

- Polymorphism of deletion in mitochondrial DNA region V among 26 Han Chinese
- Journal of Army Medical University Vol. 29, Issue 3, Pages: 191-192(2007)
- 作者机构：
  
  第三军医大学：高原军事医学系病理生理学与高原生理学教研室，全军高原医学重点实验室，基础医学部全军免疫学研究所
- 作者简介：
- 基金信息：
- DOI：
  CLC： Q343.35;R181.33;Q754
- Published：2007，
  
  Published Online：15 February 2007，
- 稿件说明：
移动端阅览
LUO YONG-JUN, GAO WEN-XIANG, GAO YU-QI, et al. Polymorphism of deletion in mitochondrial DNA region V among 26 Han Chinese. [J]. Journal of army medical university, 2007, 29(3): 191-192.
DOI：

LUO YONG-JUN, GAO WEN-XIANG, GAO YU-QI, et al. Polymorphism of deletion in mitochondrial DNA region V among 26 Han Chinese. [J]. Journal of army medical university, 2007, 29(3): 191-192. DOI：

摘要

目的测定中国汉族人线粒体DNA region V 9 bp缺失多态性频率。方法抽取26例健康无血缘关系汉族人静脉血，提取总DNA，扩增线粒体DNA region V ，并测序，测序结果与剑桥修正序列比对。结果中国汉族人线粒体DNA region V 9 bp缺失多态性出现频率为19.23％。结论汉族人线粒体DNA region V 9 bp缺失多态性出现频率高于文献报道的维吾尔族人和蒙古族人该多态性出现频率。

Abstract

Objective To determine the polymorphism frequency of deletion in mitochondrial DNA region V among Han Chinese. Methods Totally 26 unrelated health Han Chinese venous blood samples were subjected. Their total DNA was extracted

and the mitochondrial DNA region V was amplified and sequenced. The results were blasted with the revised Cambridge reference sequence (rCRS). Results The polymorphism frequency of deletion in mitochondrial DNA region V among Han Chinese was 19.23％. Conclusion The polymorphism frequency of deletion in mitochondrial DNA region V among Han Chinese was higher than the Uygur and the Mongolia’s frequencies which had been reported.

关键词

中国汉族人线粒体DNA多态性缺失

Keywords

Han Chinesemitochondrial DNApolymorphismdeletion

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Correlation of sperm mitochondrial DNA copy number and integrity with semen parameters in male adults

Correlation of CYP2C19*2 polymorphism with clopidogrel resistance and risk of stroke recurrence in Uygur patients with ischemic stroke

Role of mtDNA3010 A/G genotype variation in pathogenesis of high-altitude pulmonary edema

MSI mutation of mitochondrial DNA in lung squamous carcinoma

Related Author

WANG Yu1

GENG Jianhui1

CHEN Jian1

YANG Yidong2

CHEN Dewei2

Related Institution

Department of Medicine and Equipment for High Altitude Region, 2Key Laboratory of Extreme Environmental Medicine of Ministry of Education, 3Department of High Altitude Physiology, 4Department of Pathophysiology, Faculty of High Altitude Military Medicine, Army Medical University (Third Military Medical University)

Institute of Toxicology, College of Military Preventive Medicine, Third Military Medical University

School of Public Health and Management, Ningxia Medical University, Yinchuan, Ningxia Hui Autonomous Region

Department of Neurology, the First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang Uygur Autonomous Region

Department of Military Medical Geography, Laboratory of Military Combat Rescue Training Technology and Equipment Research and Development, Army Health Service Training Base, Army Medical University (Third Military Medical University)

⁰