Objective      To review our experience and to analyze the clinical data and treatment outcomes of pseudoaneurysm patients after femoral artery catheterization.        Methods      A retrospective review of 46 patients with pseudoaneurysm after femoral artery catheterization admitted to Southwest Hospital from January 1

2007 to March 31

2011 was conducted. Interventional diagnosis and therapy was performed. Their demographic and clinical data were collected

and the outcomes of ultrasound-guided thrombin injection after intervention and compr

ession were compared and analyzed. Clinical data showed that the median age of 46 patients was 62.1±13.5 years

and 43 patients of them were complicated with hypertension

ischemic heart disease or diabetes

and 20 of them had obesity. Among these 46 patients

32 received anticoagulants after intervention and 2 had post catheterization involving both artery and vein.       Results      Compression or ultrasound-guided compression was underwent in 21 patients

with a successful rate of 66.7%. Of the 21 patients

3 had severe complication with a complication rate of 14.3%

including pseudoaneurysm sac rupture

skin necrosis and venous thrombosis. Ultrasound-guided thrombin injection was performed in 25 patients

with a higher rate of success of 100%

and no severe complication occurred. The average hospital stay of patients using compression after PSA occurrence was significantly longer than that of those with thrombin injection (3.8±10.5

vs

1.5±0.6 d

P

<

0.05). During the median follow-up of at least 3 months

good outcome was obtained

no severe complication was found including localized infection and purulence

but PAS was reoccurred in 1 patient who receiving compression.       Conclusion      The occurrence of PAS is complex after femoral artery catheterization. A better outcome may be obtained among patient receiving thrombin injection.