Objective        To evaluate the value of the Pulsed Doppler (PW)

M-mode echocardiography (MME)

real-time three-dimensional volumetric echocardiography (RT-3DE) in the assessment of right ventricular function of the fetuses with double outlet right ventricle (DORV) or Tetralogy of Fallot (TOF).       Methods        PW

MME

and RT-3DE were performed respectively in 30 fetuses with DORV or T

OF and 30 normal fetuses in our department from December 2010 to December 2012. Data including Tei index (TI)

right ventricular end-diastolic volume (RVEDV)

end-systolic volume (RVESV)

stroke volume (SV) and ejection fraction (EF) were analyzed and compared in the 2 groups.       Results        The results of fetal right ventricular TI by PW was significantly higher in the abnormal group than in the normal group (0.48±0.09

vs

0.36±0.05

P

<

0.05). MME indicated that EF in abnormal fetuses was 60.04±7.69

while RT-3DE showed the index was 52.04±7.26

with the former significantly higher than the later (

P

<

0.05). TI by PW was consistent with in the receiver operating characteristic (ROC) curve of RT-3DE

but was significantly different from that of MME.       Conclusion        RT-3DE evaluates the right ventricular function of fetuses with complex congenital heart disease accurately without depending on any anatomical assume

with good repeatability. Due to the irregularities of the right ventricular morphology

there is a large error in ventricular diameter measurement by MME. The accuracy and repeatability of MME are lower that that of the RT-3DE.