Objective      To retrospectively analyze our experience in the diagnosis and surgical treatment of aortopulmonary septal defect (APSD) in our department on 11 patients from August 2002 to May 2013.       Methods      Eleven patients

all males at a mean age of 6.91 years (ranging from 2 to 13 years)

were diagnosed as APSD by echocardiography and multi-slice CT scanning. According to Mori classification system

type Ⅰ APSD was presented on 4 patients

whereas type Ⅰ and Ⅲ were found in 4 and 3

respectively. Five patients were associated with other cardiac defects

whereas 1 case had secondary infective endocarditis.       Results      Correct diagnosis of APSD was made in 9 cases before operation and 2 were misdiagnosed. All patients underwent surgical repair using median sternotomy

and 9 of them received cardiopulmonary bypass at moderate hypothermic temperatures

and 3 underwent got without cardiopulmonary bypass. There was no case died early

and 1 died in 28 d after operation because of severe pulmonary infection and DIC. The left 10 patients were followed up from 1 to 10 years. All of them survived with obvious remission of symptoms. Echocardiography showed there was no residual defects.       Conclusion      Echocardiography should be carried out and combined with multi-slice CT angiography or ascending aortic angiography to diagnosis of APSD before operation. Associated complex cardiovascular anomalies are closely related with operative outcomes.