To enable students to better grasp the basic skills of pathogenic biology and im-munology experimental teaching， and make full use of the characteristics of experimental teaching to train students' scientific quality and innovative consciousness， the reform of pathogenic biology and immunology experiment teaching was explored. Microbiology， Parasitology and Immunology experiment were integrated into an experimental course， and corresponding laboratory was set up to take an in-dependent experimental teaching. Through renewing experiment teaching idea， some measures were taken such as modularization and personalization of the teaching content， the establishment of a com-plete management system， writing a new experimental course to match the experiment， improving teaching methods and developing students' innovative experiments to improve their enthusiasm and in-terest for experimental class learning， thus enhancing their innovation ability.