The experiment contents were integrated into three parts such as basic skills and verification experiment， systematic experiment and designing experiment. Basic skills and confirmato-ry experiments were performed alone with theory teaching by combination of modern teaching methods and traditional teaching methods， which consisted of “speaking”（experimental principles， methods and main technical points using multimedia）， “looking”（demonstrating related operation on teaching website）， teachers' demonstration， students' doing experiment independently and summarizing. In this part， the experimental operation skills such as the sterile operation technology， staining technology， microscopy technology and pure culture were emphasized. Systemic experiments would be carried out after completion of the most theory， the experiment time could be adjusted according to the experiment content， and the PBL teaching method was taken in this stage. After the theory teaching of Medical Microbiology was finished， students voluntarily participated in design experiments in the last stage， which were the fusion of scientific research subject and the experimental teaching. From the preview experiment， experiment operation， experiment report， to the final test， the multi-dimensional evalua-tion was implemented throughout the course of experiment teaching.