According to the three orientation cultivating mode

in order to improve quality of experiment teaching in pathogen biology and cultivate innovative talents of medicine the open experi-ment teaching which based on the research projects is applied to optimize the experiment content design

teaching form and comprehensive assessment. For example

In the choice of subject direction more attention are paid to the students' autonomy; In the design of experiment content students' inter-ests should be fully considered; During the course of experiments

the teachers play the role of visitors most of the time; In the experiment evaluation

students' ability of solving problems and their innova-tive ability are included. By participating in research projects

it not only can arouse the enthusiasm of students

but also can cultivate their scientific spirit of innovation and the rigorous scientific attitude.