Objective　To investigate the effect of the clinical teaching model based on the mini-clinical evaluation exercise (Mini-CEX) scale in Department of General Surgery

and to provide a reference for improving the quality of clinical teaching in Department of General Surgery. Methods　A total of 82 nursing interns in Department of General Surgery from June 2016 to June 2018 were enrolled

among whom 41 undergraduates in 2016 were enrolled as control group and 41 undergraduates in 2017 were enrolled as intervention group. The undergraduates in the control group were taught with the traditional clinical teaching method

and those in the intervention group were taught with the clinical teaching model based on the Mini-CEX scale. The two groups were compared in terms of department examination results

score of the Mini-CEX scale

and quality assessment score of clinical nursing teaching

in order to evaluate the teaching quality in Department of General Surgery. Results　Compared with the control group

the intervention group had significantly higher department examination score [(96.56±4.23) vs. (90.42±5.12)] and total score of Mini-CEX scale [(5.22±0.45) vs. (4.01±1.03)]. The intervention group had a significantly higher excellent rate than the control group (P<0.05). The intervention group also had a significantly higher quality assessment score of clinical nursing teaching than the control group [(98.34±6.12) vs. (92.45±5.16)]. Conclusion　The clinical teaching model based on the Mini-CEX scale can improve the quality of teaching and clinical teaching skills in department of general surgery and thus improve the clinical skills and comprehensive quality of nursing interns.