Objective　To investigate the effect of applying scenario simulation practice in the professional ICU nursing students' emergency and intensive care intensified skill training before intern-ship. Methods　Totally 120 professional ICU nursing students from grade 2010 and 2011 were enrolled. Control group included 60 students from grade 2010 and experimental group included 60 students from grade 2011. Studnets in control group accepted standardized routine training while those in experimental group accepted scenario simulation practice. All students participated in skill examination after training. Two questionnaires were designed to survey nursing students and clinical teachers respectively at one month after internship. One questionnaire was to evaluate students' attitude to the training and the other one was to survey clinical teachers' evaluation of students' abilities. T test was used to statistically an-alyze skill examination performance and questionnaire scores between two groups. Results　Skill exami-nation performance of experimental group was better than that of control group （P<0.01）. Effects of in-tensified training were better in experimental group than in control group （P<0.05， P<0.01） including the aspects of combining theory and practice， shortening internship role transition time， enhancing self-confidence of clinical practice and relieving tension anxiety before practice， etc. Clinical teachers thought that the experimental group's analysis ability， strain capacity， operation ability， communication ability， team cooperation ability and actively acquiring knowledge ability were stronger than those of control group（P < 0.01）. Conclusions　Scenario simulation practice is helpful to improve operation ability and comprehensive ability. Nursing students can adapt to the clinical work better. Findings may be bene-ficial to the improve-ment of teachers' professional level.