Teachers introduced the means of the scientific thinking and scientific research prac-tice in the curriculum of proteomics in order to train the postgraduates to joint the theory and the practical research work in the curriculum course. For example， to cultivate students to truly understand the 2-DE protein separation technique， teachers used the various proteomic profile obtained from our research to points out its problems and limitations based on the classical 2-DE， then compared the improved 2-DE protein separation chromatography with the classical 2-DE graphic and analyzed what is the problem and how to solve them in the practical work. To improve the ability of scientific thinking for postgraduates， teachers took the tumor as the teaching cases and asked the postgraduates to search the references of can-cer associated with their professional， to put forward the scientific problems based on carefully reading these references， to design their research project and to seek the answer to their issue. These new teaching methods were found to be beneficial in training scientific talents of medical postgraduates.