Current curriculum provision and teaching patterns of computer science in medical school has been far behind the requirements of clinical and research works， which restricted the develop-ment of medical talents to a large extent. According to the experiences of teaching practice， Department of Computer Science in Chongqing Medical University launched reform on medical computer science from aspects of teaching practice， curriculum provision， teaching methods and evaluation methods. Computer courses were opened according to students' computer knowledge and the profession. Task-based teaching and comprehensive evaluation methods were employed in order to improve the teaching quality.