This paper analyzed challenges and difficulties in the teaching of academic English for doctoral postgraduates. The ideas of putting emphasis on listening and speaking course of academic English， compiling suitable teaching material， encouraging teachers to advance against the hardship were proposed. At the same time， it took China pharmaceutical university as an example to discuss the practice of listening and speaking course of pharmaceutical English for doctoral postgraduates and summed up the experiences in the enaction of teaching objectives， curriculum provision， compilation of teaching material， design of teaching model， etc. The purpose was to provide experiences for teach-ing reform of listening and speaking course of pharmaceutical English.