Objective　To explore the effect of problem-based learning（PBL） in emergency clinic skill training. Methods　Totally 65 students participating in emergency clinical skill training in The Ninth People's Hospital of Shanghai Jiao Tong University were enrolled. Thirty-three 2008 grade five-year clinic majors as control group were taught by traditional teaching method while Thirty-two 2009 grade five-year clinic majors as experimental group were taught by PBL. After the courses， final examinations （theoretical exam， case analysis and skill appraisal） and questionnaire survey were used to evaluate the teaching effectiveness between the two groups. Data were managed by SPSS 13.0 soft-ware package. Quantitative data between two groups were compared by t-test. Enumeration data between two groups were compared by chi-square test. Results　There was no difference in theoretical score between two groups（P=0.212）. Scores of case analysis and skill appraisal in experimental group were higher than those in control group（P<0.05）. There were significant differences between experimental group and control group in arousing students' learning interest， promoting understanding of knowledge， cultivating clinical comprehensive ability， increasing communication skills， improving team coopera-tion ability and clinical operating ability（P<0.05）. Conclusions　PBL mode is better than traditional teaching methods in emergency clinical skill training. PBL can improve students' clinical comprehen-sive ability and emergency operations can be perfectly applied in clinic typical cases.