A teaching method called cross-disciplinary joint teaching， which integrated the neural system-based physiology， anatomy and histology from gross morphology to microstructure， then to physiological function， was carried out on 2010 clinical eight-year program medical students. Joint-teaching method was carried out throughout the whole courses. That means in three subjects related to the discipline， teachers compile the textbook， discuss teaching scheme， compile cases， collectively prepare lessons， and attend lectures and discussion together. Flexible teaching forms such as case-based teaching， problem-based teaching and bilingual teaching were also run through the whole pro-cesses of the teaching. Compared with the traditional teaching model， cross-disciplinary joint teaching not only achieves the integration of morphology， microstructure and functions of nervous system， but also has a priority of helping the students to develop a more efficient learning ability such as initiative study and thinking extension.