Objective　This study aimed to accurately understand medical teaching design re-search status and development trend to provide practical basis for the future of the medical teaching practice. Methods　CNKI academic journal articles from January 1

2000 to December 30

2013 were retrieved

using search item for the “subject”

the retrieval word for “instructional system design” or “instructional design”

and the retrieval “subject” for “medicine”

and matches are “precise” retrieval way

and a total of 298 articles were retrieved. The common word analysis method was used to compare the high frequency keywords

analyze the key words in the article

and study the high frequency key-words clustering. Results　In the two stages from 2000 to 2006 and from 2006 to 2013

research on medical teaching design of the courseware

distance education and other traditional E-learning-fre-quency gradually reduced

and vocabulary frequency related to education informationization of new situation such as cooperative learning

teacher education and constructionism and so on increased. In addition

in the second stage

some fresh words related to new technologies and new media appeared

such as interactive electronic whiteboard

virtual reality technology and so on. According to the corre-lation of keywords in 2007-2013

we found that the current medical teaching design research mainly gathered in three aspects such as classroom teaching

information technology supporting the reform of medical teaching and the training of medical teaching practitioners. Conclusion　The research con-cluded that today and the future of medical teaching design research will mainly focus on three as-pects such as effective teaching

the diversification of teaching supported by information technology and open medical education research under the Internet environment.