Objective To explore the application of the evidence-based case report method in the standardization training of resident physicians at department of endocrinology. Methods Fifty-one residents recruited from the endocrinology department were randomly divided into the experiment group (26 cases) and control group (25 cases). The evidence-baced case report method was conducted in the experimental group

and the traditional clinical teaching mode was applied in the control group. The results of the examination of two groups including the theoretical test and skill test were compared and the questionnaire survey was conducted to find out the differences of students' interest in learning

clinical skills and satisfaction. All data were compared using t test. Results There was no significant difference in theoretical test between the two groups (P> 0.05). The total score of the skill test in the experimental group was (85.13 ± 4.63) and the control group (76.79 ± 3.11) (P = 0.000). The students in the experimental group showed that the teaching method had more significant effects on improving their learning interest and initiative

clinical thinking ability

clinical work ability

literature review ability and medical article writing ability. Scores of satisfaction with teaching methods (total score was 10) for experimental group were (9.69 ± 0.34)

which was also significantly higher than those in the control group (8.01 ± 0.39) (P = 0.000). Conclusion The application of evidence-based case report teaching method in the standardized training of resident physicians in department of endocrinology is worthy of being perfected and further popularized in clinical teaching work.