Objective To evaluate the effectiveness and to access the feasibility in the case based learning (CBL) to the course of emergency and critical care nursing. Methods 120 undergraduates of emergency and critical care nursing were randomly divided into two groups called CBL group and traditional group. The CBL group's students were provided a representative case which was consider as core of the whole learning process. After collecting relevant data and comprehending the process of treatment

teachers would summarize in the end. As for traditional groups

students would have a complete clinical skills training according to the standardized training requirements of the residents. The two groups were evaluated systematically after six months of different teaching methods. Results CBL group showed the more desirable effect than traditional group not only in written score [(92.5±3.0) vs. (85.3±3.3)] and clinical skills score [(93.1±4.5) vs. (88.1±3.4)] but also in deepening the understanding of diseases and strengthening the communication ability between doctors and patients. Conclusion The CBL method applied to clinical teaching of undergraduates of emergency and critical care nursing could significantly promotes the effect of teaching and the quality of student.