Objective To explore the value of ex vivo porcine stomach model for endoscopic submucosal dissection training for international trainees. Methods Fifteen international students received ESD training and learning for twenty days. Firstly

students learned basic theory of ESD and completed a questionnaire. Then they were randomized to receive endoscopic training either on the vitro animal (group A) or on training experience (group B) of the clinical observation. At last

one case was assessed by an experienced endoscopist. The total and step-by-step operating time

complete resection

size of specimen and complications were recorded. All students completed the questionnaire once again. Data analysis used SPSS 20.0. Results The total time of group A and group B have statistical difference. There were significant differences between the two groups on cutting time and dissection time

but there were no difference on marking time

injection time and operating speed. There was only one case of block resection and perforation in each group. For group A

their mastery and clinic confidence of ESD had been obviously increased after the animal training course. Compared with the operation before the training in group A

it was found that the total time and cutting time of the ESD after the training were also significantly improved. Conclusion Theory combined with endoscopic training on vitro animal model can make the students familiar with the basic theory and master，which is helpful and valuable for them to perform ESD in further clinic practice.