Objective　To explore the application effect of disease-oriented digitalized teaching model in the undergraduate teaching of stomatology. Methods　A total of 34 undergraduate students in clinical medicine from Batch 2018 were selected as the control group 1

24 undergraduate students in stomatology from Batch 2015 were selected as the control group 2

and 23 undergraduate students in stomatology from Batch 2018 were collected as the experimental group. The two control groups all accepted the traditional teaching mode

and the experimental group accepted the disease-oriented digitalized teaching model. Finally

the teaching effect was evaluated through questionnaire surveys and less difficult oral professional tests. The SPSS 24.0 was used to conduct t test. Results　After accepting this teaching model

students improved their understanding of the concept of organism and disease (P<0.05)

and they had a positive evaluation of this teaching model. It was found that the tests scores of the experimental group (42.17±1.21) were significantly higher than those of non-dental major students of the same Batch (24.71±1.42) (P<0.05)

with significant differences

while without significant difference between the tests scores of the senior stemmatological students (43.33±1.30) (P>0.05). Conclusion　This teaching model enables students to establish the concept of organism and form a disease-oriented knowledge framework before entering the decentralized professional courses

which may further stimulates the interest of junior students in their majors

and enhances their professional awareness compared with traditional teaching model. It's also a useful exploration for teaching hospitals to conduct teaching activities of junior undergraduates outside the classroom.