Objective　To investigate the application of case-based learning (CBL) combined with evidence-based learning (EBL) teaching in clinical teaching of oncology. Methods　Totally 57 resident doctors were divided into experimental group and control group. The experimental group received CBL and EBL teaching

and the control one received lecture-based learning (LBL) teaching. The teaching effect was evaluated by examination and questionnaire

and the data were analyzed by SPSS 20.0. Results　The examination scores of the experimental group and the control group were (85.393±7.213) and (81.276±8.035)

and the ones of case analysis were (34.393±2.485) and (32.379±3.005) respectively. Meanwhile

questionnaire survey showed that the evaluations of experimental group were significantly better than those of the control one in promoting learning interest and initiative

retrieval ability

self-learning ability

clinical thinking and learning efficiency (P<0.05). Conclusion　The teaching effect of integration of CBL and EBL is better than LBL.