Objective　To explore the value of ex-vivo porcine stomach model for endoscopic submucosal dissection (ESD) training for international trainees. Methods Fifteen international students received ESD training and learning for twenty days. Firstly

students learned basic theory of ESD and completed a questionnaire. Then they were randomized to receive endoscopic training either on the vitro animal (group A) or on training experience (group B) of the clinical observation. At last

one case was assessed by an experienced endoscopist. The total and step-by-step operating time

complete resection

size of specimen and complications were recorded. All students completed the questionnaire once again. SPSS 20.0 was used for t test and chi-square test. Results There was significant difference in total ESD operation time between group A and group B (P＜0.05). There were significant differences between the two groups on cutting time and dissection time

but there was no difference on marking time

injection time and operating speed. There was only one case of block resection and perforation in each group. For group A

their mastery and clinic confidence of ESD had been obviously increased after the animal training course. Compared with the operation before the training in group A

it was found that the total time and cutting time of the ESD after the training were also significantly improved. Conclusion　Theory combined with endoscopic training on vitro animal model can make the trainees familiar with the basic theory and master the operational skills

which is helpful and valuable for them to perform ESD in further clinic practice.