Objective　To explore the teaching effect of case-based learning (CBL) teaching combined with high-fidelity simulation (HFS) system training mode in first aid skills training for postgraduates majoring in pediatrics. Methods　In this study

200 pediatrics graduate students in emergency clinical rotation were randomly divided into 4 groups: control group

traditional lecture teaching combined with simple simulation training; CBL group

CBL case combined with simple model training; HFS group

traditional lecture teaching combined with high-fidelity simulation training; CBL+HFS group

CBL case combined with high-fidelity simulation training. All the data were statistically analyzed with STATA 14.0 software. Results　Recent assessment results showed that in cardiopulmonary resuscitation

electroshock therapy

tracheal intubation skills

the average score of the CBL group was higher than that of the control group

and the average score of the HFS group was higher than that of the control group

with statistically significant differences (P<0.05). In terms of non-technical ability

the average score of CBL group was higher than that of control group

and that of HFS group was higher than that of control group

with statistically significant differences (P<0.05). There was interaction and cooperation between CBL and HFS

and the analysis results of the long-term assessment results were the same as those of the short-term assessment results. Conclusion　CBL combined with HFS is helpful to improve the first aid technical ability and non-technical ability of postgraduates majoring in pediatrics

which is worth further popularizing.