Objective　To apply CBL combined with PBL based on SMART (specific

measurable

attainable

relevant and time-based) principle in nursing practice teaching in radiotherapy. Methods　A total of 100 nurses who performed nursing practice in the Department of Radiotherapy in Guangdong Provincial Hospital of Traditional Chinese Medicine from May 2016 to May 2020 were selected as the research objects. They were divided into a control group and a study group according to their admissions

with 50 people in each group. The study group used CBL combined with PBL teaching based on SMART principle

and the control group used traditional practice teaching. After the clinical practice

the two groups were assessed on theoretical and clinical practice skills

and the two groups' teaching satisfaction and teaching effects were evaluated through seminars and questionnaire surveys. SPSS 22.0 was used for t test and chi-square test. Results　The theoretical and clinical practice performance assessment scores of the practical nurses in the study group were higher than those in the control group

with statistically significant differences (P<0.001). The teaching satisfaction rate of the practice nurses in the control group was 62.00% (31/50)

and that of the practice nurses in the study group was 96.00% (48/50)

with significant differences (P<0.001). In terms of improving independent learning ability

information acquisition and problem analysis ability

improving clinical thinking ability

mobilizing learning enthusiasm

enhancing teamwork ability

nurse-patient communication ability

and recognition of innovation ability

the teaching satisfaction of the research group was higher than that of the control group. Conclusion　The application of SMART principle in teaching has the advantages of clear goals and quantifiable evaluation. The combination of CBL and PBL based on SMART principle can help to improve the mastery of theoretical and practical skills of radiotherapy practice nurses

and achieve satisfactory teaching results.