THE DIAGNOSTIC VALUE OF DIRECT IMMUNOFLUORESCENCE TEST FOR PEMPHIGUS

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THE DIAGNOSTIC VALUE OF DIRECT IMMUNOFLUORESCENCE TEST FOR PEMPHIGUS

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- THE DIAGNOSTIC VALUE OF DIRECT IMMUNOFLUORESCENCE TEST FOR PEMPHIGUS
- Journal of Chongqing Medical University Issue 3, Pages: 210-212(1985)
- 作者机构：
  
  1. 重庆医学院第一医院皮肤科
  2. 重庆医学院病理解剖教研室
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：1985，
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[1]袁承晏,高永良,刁友芳,章高炎.直接免疫荧光检查对天疱疮的诊断价值[J].重庆医学院学报,1985(03):210-212+234.

THE DIAGNOSTIC VALUE OF DIRECT IMMUNOFLUORESCENCE TEST FOR PEMPHIGUS. [J]. Journal of Chongqing Medical University (3):210-212(1985)
[1]袁承晏,高永良,刁友芳,章高炎.直接免疫荧光检查对天疱疮的诊断价值[J].重庆医学院学报,1985(03):210-212+234. DOI：

THE DIAGNOSTIC VALUE OF DIRECT IMMUNOFLUORESCENCE TEST FOR PEMPHIGUS. [J]. Journal of Chongqing Medical University (3):210-212(1985) DOI：

摘要

本文报道10例天疱疮患者的直接免疫荧光检查结果。10例的荧光均发生在表皮棘细胞膜之间

全层弥漫

呈蜂窝状。红斑型及落叶型的荧光以表皮浅层最为明显。疱腔内脱落的棘层松解细胞也显示同样的荧光。免疫球蛋白的类型

10例都有lgG

与文献报道者相符。有1例落叶性天疱疮除lgG之外

尚有lgM的存在

其意义尚不明瞭。有3例寻常性天疱疮出现C

的沉积

推测可能是组织损伤的继发性结果。结果表明

直接免疫荧光检查对大疱性疾病的诊断是很有价值的

特别是单纯累及粘膜的大疱性疾病

更有帮助。

Abstract

This paper reports the results of direct immunofluorescence(DIF)test in 10 patients with pemphigus. In all the biopsied samples

the fluorescence is observed in the intercellular space of the stratum spinosum

diffusely distributed in the whole layer in the form of a honeycomb. The fluorescence of erythematous type and foliaceous type was most prominent in the superficial layer of epidermis. The acantholytic cells exfoliated in the bulla also showed the same fluorescence. By means of immunofluor-escence test

IgG was identified in all cases

a result identical with reports in the literature

In one case of pemphigus foliaceus

in addition to IgG

there also occurred IgM

the significance of which was unknown. C3 deposits were found in 3 cases of pemphigus vulgaris. It was suspected that this change might be the secondary result of tissue injuries. The results indicated that DIP test is very valuble in the diagnosis of bullous dermatoses; especially In those cases which have lesions on the mucous me mbrane only.

关键词

天疱疮免疫荧光

Keywords

PsoriasisImmunofluorescence

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