THERAPEUTIC EFFECT OF AMIODARONE IN THE TREATMENT OF CARDIAC ARRYTHMIA IN CHILDHOOD-AN ANALYSIS OF 30 CASES. [J]. Journal of Chongqing Medical University (4):255-258(1985)
THERAPEUTIC EFFECT OF AMIODARONE IN THE TREATMENT OF CARDIAC ARRYTHMIA IN CHILDHOOD-AN ANALYSIS OF 30 CASES. [J]. Journal of Chongqing Medical University (4):255-258(1985)DOI:
THERAPEUTIC EFFECT OF AMIODARONE IN THE TREATMENT OF CARDIAC ARRYTHMIA IN CHILDHOOD-AN ANALYSIS OF 30 CASES
摘要
乙胺碘呋酮治疗小儿快速型心律失常30例。年龄最小1(7/30)月
最大13岁。疗效显著
特别是近期有效率93.3%
其中3例静脉用药治疗阵发性室上性心动过速2例显效迅速。经随访部分早搏病例有复发
但再用或加至原剂量仍有效
维持用药最长16月。口服副作用小
有心动过缓
心电图P-R或Q-T间期延长、皮疹、恶心、眼角膜微粒沉着及光晕感
未发现甲状腺功能明显变化。1例静脉注射发生完全性房室传导阻滞、血压下降等严重反应
故强调静脉用药应严格控制剂量及速度、心肌病、心脏肥大者相对禁用。
Abstract
A series of 30 cases of cardiac tachyarrythmia were treated with amiodarone. The minimal agewas month
the maximal was 13 years. It showed significant therapeutic effect
especiallythe recent effectiveness was 93.3%. Among 3 cases of paroxysmal supraventricular tachycardia treated with amtodarone intravenously
2 cases showed rapid therapeutic effect. After follow-up part of the premature contractions relapsed
but they disappeared after readministration or restoring to original dose. The longest maintenance period was 16 months. A few side effects could be observed during oral amiodarone. They were bradycardia
prolonged PR or QT interval
rash
nausea
corneal microdeposits and seeing halos arround lights. No significant disturbance of thyroid function was observed. 1 case of complete atrioventricular block and hypotension occured after intravenous amiodarone. It was emphasized that the dosage and speed of the drug should be controlled during intravenous administration. It was relatively contraindicated in cases of cardiomyo-pathy and cardiomegaly.