A DIRECT METHOD TO OBTAIN CHROMOSOME METAPHASE FROM HUMAN CHORIONIC VILLI

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A DIRECT METHOD TO OBTAIN CHROMOSOME METAPHASE FROM HUMAN CHORIONIC VILLI

更新时间：2024-01-17

- A DIRECT METHOD TO OBTAIN CHROMOSOME METAPHASE FROM HUMAN CHORIONIC VILLI
- Journal of Chongqing Medical University Issue 2, Pages: 157-160(1985)
- 作者机构：
  
  重庆医学院妇产科遗传室研究生
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：1985，
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[1]彭勤.绒毛膜细胞染色体直接制备法[J].重庆医学院学报,1985(02):157-160.

A DIRECT METHOD TO OBTAIN CHROMOSOME METAPHASE FROM HUMAN CHORIONIC VILLI. [J]. Journal of Chongqing Medical University (2):157-160(1985)
[1]彭勤.绒毛膜细胞染色体直接制备法[J].重庆医学院学报,1985(02):157-160. DOI：

A DIRECT METHOD TO OBTAIN CHROMOSOME METAPHASE FROM HUMAN CHORIONIC VILLI. [J]. Journal of Chongqing Medical University (2):157-160(1985) DOI：

摘要

绒毛膜细胞直接法制备染色体是一种新的早期产前诊断方法。本文用改良方法直接制备染色体

减少染色体丢失现象

获得较满意效果。本法资料表明分裂相出现率为100%

可进行核型分析者达94%

适用于6～11周孕妇

特别是孕7周左右效果更好。与绒毛膜细胞培养法相比

受母体细胞污染的可能性小

结果更可靠。此方法简单、快速、效果好、易于普及

对产前诊断提供了有效措施。

Abstract

The direct method to obtain chromosome metaphase from human chorionic villi is a new method of early prenatal diagnosis. Our modified method for preparing the chromosome obtained a satisfactory result. It indicated that the cases of metaphase appearance were 100%

and the cases of fetal karyotype were 94%. This method used in 6th to llth week of preganacy

especially 7th week were suitable and it is more reliable to compare with the method of chorionic villi cell culture

since the possibility of contamination of maternal cell is so amall. T his method is easy

fast

effective and easy to control to be populated for early prenatal diagnosis .

关键词

染色体绒毛产前诊断

Keywords

ChromosomeChorienic Villiprenatal diagnosis

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