ANTICANCER DRUG SENSITIVITY TEST BY MTT COLORIMETRIC ASSAY FOR THORACIC TUMOR

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ANTICANCER DRUG SENSITIVITY TEST BY MTT COLORIMETRIC ASSAY FOR THORACIC TUMOR

更新时间：2024-01-17

- ANTICANCER DRUG SENSITIVITY TEST BY MTT COLORIMETRIC ASSAY FOR THORACIC TUMOR
- Journal of Chongqing Medical University Issue 1, (1994)
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  CLC： R979.1
- Published：1994，
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[1]秦治明,张泽普,李良彬, 骆云鹏,汤为学,王瑞雪.43例胸部恶性肿瘤的抗癌药敏试验（MTT法）测试结果分析[J].重庆医科大学学报,1994(01):36-39.

ANTICANCER DRUG SENSITIVITY TEST BY MTT COLORIMETRIC ASSAY FOR THORACIC TUMOR. [J]. Journal of Chongqing Medical University (1).(1994)
[1]秦治明,张泽普,李良彬, 骆云鹏,汤为学,王瑞雪.43例胸部恶性肿瘤的抗癌药敏试验（MTT法）测试结果分析[J].重庆医科大学学报,1994(01):36-39. DOI：

ANTICANCER DRUG SENSITIVITY TEST BY MTT COLORIMETRIC ASSAY FOR THORACIC TUMOR. [J]. Journal of Chongqing Medical University (1).(1994) DOI：

摘要

本文用ＭＴＴ法对４３例胸部恶性肿瘤，其中肺癌３７例（含肺癌胸水１０例），食管癌６例进行了体外抗癌药敏检测．实验成功率肺癌实体瘤为９２．７％，食管癌为８３．３％，肺癌胸水为１００％。检测了恶性肿瘤对顺铂、卡铂、丝裂霉素－Ｃ、鬼臼乙叉甙、表阿雹素、长春新碱、５－氟脲嘧啶、放线菌索－Ｄ和平阳霉素等多种抗癌药物的敏感性。结果表明，同一肿瘤的不同病理类型对同一抗癌药物的敏感性各异，同一病理类型的不同个体对同一抗癌药物的敏感性也不同。

Abstract

3 samples of thoracic tumor(27 of the lung solid tumor

10 of the pleural effusion

6 of theesophagus)were tested by MTT assay. The measurable rate of lung solid tumor was 92.7% and thatof esophagul cancer was 83.3%

100% of the plueral effusion . Results showed that differentsensitivities were tested for the fresh tumor spccimens to agents (CDDP、 CBDCA、 MMC、VP-16、EDR、VCR、5-Fu、ActD and PYM). The results signify that sensitivity of the different tumortypes and different individuals of the same tumor type varies.

关键词

MTT法抗癌药敏试验胸部恶性肿瘤

Keywords

MTT colorimetric assayAnticancer drug sensitivityThoraeic tumor

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