APPLICATION OF SERUM ACUTE PHASE PROTEINSAND EBV IgA/VCA,IgA/EA DETERMINATION IN DI- AGNOSIS OF NASOPHAKYNGEAL CARCTNOMA

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APPLICATION OF SERUM ACUTE PHASE PROTEINSAND EBV IgA/VCA,IgA/EA DETERMINATION IN DI- AGNOSIS OF NASOPHAKYNGEAL CARCTNOMA

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- APPLICATION OF SERUM ACUTE PHASE PROTEINSAND EBV IgA/VCA,IgA/EA DETERMINATION IN DI- AGNOSIS OF NASOPHAKYNGEAL CARCTNOMA
- Journal of Chongqing Medical University Issue 1, (1996)
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  CLC： R739.63
- Published：1996，
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[1]王丽洪,袁兴玉,陈佩君.血清急性期蛋白EB病毒IgA／VCA，IgA／EA抗体测定在鼻咽癌诊断中的应用[J].重庆医科大学学报,1996(01):35-39.

APPLICATION OF SERUM ACUTE PHASE PROTEINSAND EBV IgA/VCA,IgA/EA DETERMINATION IN DI- AGNOSIS OF NASOPHAKYNGEAL CARCTNOMA. [J]. Journal of Chongqing Medical University (1).(1996)
[1]王丽洪,袁兴玉,陈佩君.血清急性期蛋白EB病毒IgA／VCA，IgA／EA抗体测定在鼻咽癌诊断中的应用[J].重庆医科大学学报,1996(01):35-39. DOI：

APPLICATION OF SERUM ACUTE PHASE PROTEINSAND EBV IgA/VCA,IgA/EA DETERMINATION IN DI- AGNOSIS OF NASOPHAKYNGEAL CARCTNOMA. [J]. Journal of Chongqing Medical University (1).(1996) DOI：

摘要

测定１９０例鼻咽癌（ＮＰＣ）患者血清中急性期蛋白（ＡＰＰＳ）包括：唾液酸（ＳＡ）．α＿１－抗胰蛋白酶（α＿１－ＡＴ），α＿１－酸性糖蛋白（ａα＿１－ＡＧＰ），触珠蛋白（ＨＰ），铁传递蛋白（ＴＦ）和前清蛋白（ＰＡ）及ＥＢ病毒（ＥＢＶ）ＩｇＡ／ＶＣＡ，ＩｇＡ／ＥＡ抗体，并评价ＡＰＰＳ和ＥＢＶＩｇＡ／ＶＣＡ，ＩｇＡ／ＥＡ抗体对鼻咽癌的诊断价值。。将ＡＰＰＳ测定值经逐步判别分析统计学处理，求得判别函数，用以对ＮＰＣ进行判别诊断。结果发现：ＮＰＣ治疗前组ＡＮＰＳＥＢＶＩｇＡ／ＶＣＡ，ＩｇＡ／ＥＡ与临床病理诊断的符合率分别为８１．８８％和５６．５７％，而治疗后未复发组两者的符合率分别为８０．９５％和３３．３３％。结果表明：对ＮＰＣ的诊断和随访ＡＰＰＳ优于ＥＢＶＩｇＡ／ＶＣＡ，ＩｇＡ／ＥＡ抗体。

Abstract

To evaluate the diagnostic value of acute phase proteins(APPS)and EBV IgA/VCA

IgA/EA for nasopharyngeal carcinoma(NPC)

the serum APPs including sialic acid(SA)

al-antit- rypsin(a1-AT)

a1-acidyglycoproteins(a1-AGP)

Haptoglobin(HP)

Transferrin(TF)

and preal-bumin(PA)and EBV IgA/VCA

IgA/EA were determinated in 190 patients with NPC.The dis-criminatnt function equations

with wich the disriminant diagnosis for NPC was ’made

were obtamed by stepwise discriminant analysis with APPs.It was found that in pretreated NpC group the agreement rates of APPs and EBV-IgA/ VCA

IgA/EA with clinical patholgical diagnosis were 81.88 % and 56.57% respoctively

but in treated caseswithout evidence of recurrence were 80.95 % and 28.57 % respectively. Our results suggested that the APPs werebetter than EBV IgA/VCA

IgA/EA for diagnosis and follow-up of NPC.

关键词

鼻咽癌急性期蛋白EBV抗体

Keywords

Nasopharyngeal carinomaAcute phase proteinsEpstein-Barr virus antibodies

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Diagnostic value of sialic acid and acute phase proteins for laryngeal carcinoma

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