TUMOR NECROSIS FACTOR AND INTERLEUKIN 2IN APLASTIC ANEMIA

Luo Yunping; et al

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TUMOR NECROSIS FACTOR AND INTERLEUKIN 2IN APLASTIC ANEMIA

更新时间：2024-01-17

- TUMOR NECROSIS FACTOR AND INTERLEUKIN 2IN APLASTIC ANEMIA
- Journal of Chongqing Medical University Issue 2, (1994)
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  CLC： R556.5
- Published：1994，
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[1]罗云萍,黄宗干,曹唯希.再生障碍性贫血白细胞介素2和肿瘤坏死因子的改变[J].重庆医科大学学报,1994(02):121-122+120.

Luo Yunping, et al. TUMOR NECROSIS FACTOR AND INTERLEUKIN 2IN APLASTIC ANEMIA. [J]. Journal of Chongqing Medical University (2).(1994)
[1]罗云萍,黄宗干,曹唯希.再生障碍性贫血白细胞介素2和肿瘤坏死因子的改变[J].重庆医科大学学报,1994(02):121-122+120. DOI：

Luo Yunping, et al. TUMOR NECROSIS FACTOR AND INTERLEUKIN 2IN APLASTIC ANEMIA. [J]. Journal of Chongqing Medical University (2).(1994) DOI：

摘要

本文检测了一组再生障碍性贫血患者血浆和细胞诱生的肿瘤坏死因子（ＴＮＦａ）和细胞诱生上清的白细胞介素２（ＩＬ－２）。与正常对照比较，再障病人血浆和细胞诱生上清的ＴＮＦａ活性水平明显增高（Ｐ＜０．０１），ＩＬ－２的诱生水平也明显增高（Ｐ＜０．０５），本研究提示ＴＮＦａ和ＩＬ－２在再障的发病中可能有一定的作用。

Abstract

n order to clarify the role of interleukin 2(IL-2)and tumor necrosis factor alpha(TNFα)in thepathogenesis of aplastic anemia

IL-2 and TNFα level was determined in patients with aplasticanemia. In comparison with normal subjects

TNFα activity was significantly elevated

(P<0.01)andIL-2 level increased also.(P<0.05) It is suggested that abnormal level of TNFα and IL-2 in patientswith aplastic anemia is probably related to the pathogenesis of aplastic anemia.

关键词

肿瘤坏死因子白细胞介素2再生障碍性贫血

Keywords

Aplastic anemiaInterleukin-2Tumor necrosis factor

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