8 cases of cervical condyloma(CC)and 46 cases of cervical carcinoma were studied toinvestigate the accuracy of different methods in diaguosis of CC and the relationship between CCand cervical carcinoma Papillomavirus infections were detected by means of cytologicalsmears

colpocopic and pathologic examinations

imunohistochemistry

electron microscopic ex-amination and Southern blot DNA hybridization The detection rate of CC by smears withkoilocytosis was 70.83%.39 cases of vular &/or vaginal condylomata were diagnosed in the periodof this study and by colposcopic

pathologic examination。21 cases proved to have CC。Byimmunohistochemistry

HPV-Ag was detected in 63.15%of simple CC.HPV-DNa sequences weredetected in 42.1%of CC and 85% of cervical cancers.Routine colposcopic examination and biopsyshould be taken for patients with vulvar&/or vaginal condyloma and those with abnormalcervical smears.