DISTRIBUTION AND SIGNIFICANCE OF MY- OEPITHELIAL CELLS IN BENION AND MA- LIGNANT LESIONS OF THE BREAST-IM- MUNOHISTOCHEMICAL AND ULTRASTRUC-TURAL STUDY

Zhang Hui; et al

您当前的位置：

首页 >

文章列表页 >

DISTRIBUTION AND SIGNIFICANCE OF MY- OEPITHELIAL CELLS IN BENION AND MA- LIGNANT LESIONS OF THE BREAST-IM- MUNOHISTOCHEMICAL AND ULTRASTRUC-TURAL STUDY

更新时间：2024-01-17

- DISTRIBUTION AND SIGNIFICANCE OF MY- OEPITHELIAL CELLS IN BENION AND MA- LIGNANT LESIONS OF THE BREAST-IM- MUNOHISTOCHEMICAL AND ULTRASTRUC-TURAL STUDY
- Journal of Chongqing Medical University Issue 1, (1996)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：
  CLC： R737.9
- Published：1996，
扫描看全文
[1]张徽,米粲,李园园.肌上皮细胞在乳腺良、恶性病变中的分布及意义──免疫组织化学及超微结构研究[J].重庆医科大学学报,1996(01):5-9.

Zhang Hui, et al. DISTRIBUTION AND SIGNIFICANCE OF MY- OEPITHELIAL CELLS IN BENION AND MA- LIGNANT LESIONS OF THE BREAST-IM- MUNOHISTOCHEMICAL AND ULTRASTRUC-TURAL STUDY. [J]. Journal of Chongqing Medical University (1).(1996)
[1]张徽,米粲,李园园.肌上皮细胞在乳腺良、恶性病变中的分布及意义──免疫组织化学及超微结构研究[J].重庆医科大学学报,1996(01):5-9. DOI：

Zhang Hui, et al. DISTRIBUTION AND SIGNIFICANCE OF MY- OEPITHELIAL CELLS IN BENION AND MA- LIGNANT LESIONS OF THE BREAST-IM- MUNOHISTOCHEMICAL AND ULTRASTRUC-TURAL STUDY. [J]. Journal of Chongqing Medical University (1).(1996) DOI：

摘要

６５例乳腺良性病变，１０４例乳腺癌用抗肌特异性肌动蛋白（ＭＳＡ）、抗角蛋白１４（ＣＫ－１４）和Ｓ一１００蛋白识别肌上皮细胞（ＭＥＣ）。结果：所有良性病变中的ＭＥＣ同时表达ＭＳＡ、ＣＫ－１４、Ｓ－１００蛋白，少量腔上皮细胞亦表达ＣＫ－１４和Ｓ－１００蛋白。９８例浸润性乳腺癌中，９１例（９２．８％）仅见个别ＭＳＡ阳性ＭＥＣ或完全缺如，７例（７．２％）仅见少量ＭＥＣ，对９例乳腺良性病变及２３例乳腺癌进行超微结构观察，结果与ＭＳＡ免疫组化相符。研究表明，乳腺癌中ＭＥＣ为残留成分。ＭＳＡ免疫组化染色在鉴别硬化性乳腺病和浸润性导管癌；管内乳头状瘤和乳头状癌具有实用价值。

Abstract

Ixty-five benign conditions and 104 cases of breast carcinoma were collected.Antibodies utilized to identifyMEC in this study included anti-musele-specific actin(MSA).anti一Cytokeratin-14(CK-14)and anti一S-100protein. MEC expoosed MSA

CK-14 and S-100 protein in all benign lesions examined.A small number of luminalepithelial cells alse expresseLd CK-14 and / or S-100 protein. of the 98 cases of infiltheting carcinoma of thebreast

MSA positively stained MEC wenf totally or nealy absent in 91(92.81%)cases

oniy few positive cells weredetected in 7(7.2%)cases. 9 cases of benign lesions of the breast and 23 cases of the breast carcinoma werestudied ultrastructually.The findingr of the MEC in the breast lesions were consistent with the MSA inununostainingresults. Our data indicate that the MEC of the breast carcinoma may represent the residual elements.The results alsosuggest that MSA immunostain may have practical value in distinguishing sclerosing adenosis or infiltrating ductalcarcinoma

and intraductal papillom or papillary carcinoma.

关键词

肌上皮细胞乳腺癌免疫组织化学超微结构

Keywords

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

ANGIOMATOID MALIGNANT FIBROUS HISTIOCYTOMA

DISTRIBUTION AND SIGNIFICANCE OF BASEMENT MEMBRANE IN BENIGN AND MALIGNANT LESIONS OF THE BREAST: IMMUNOHISTOCHEMICAL AND UITRASTRUCTURAL STUDY

ULTRASTRUCTURAL OBSERVATION OF LEISHMANIA DONOVANI OF HUMAN KALA-AZAH

ULTRASTRUCTURAL STUDY ON A CASE OF HAIR CELL LEUKAEMIA TREATED WITH HUMAN LEUKOCyTE INTERFERON

YOLK SAC TUMUR IN CHILDREN

Related Author

罗子国

李圆圆

米粲

向理科

唐颖

米粲

徐晨

Li Xuexian

Related Institution

重庆医科大学电镜室

重庆医科大学病理学教研室

Department of General Medicine, First Hospital)Li Weixin, et al

重庆医科大学第一医院电镜室

Department of Internal Medicine, The First Hospital

⁰