THE EXPRESSION ON DESMIN,VIMENTIN AND ACTIN IN MYOGENIC TUMORS

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THE EXPRESSION ON DESMIN,VIMENTIN AND ACTIN IN MYOGENIC TUMORS

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- THE EXPRESSION ON DESMIN,VIMENTIN AND ACTIN IN MYOGENIC TUMORS
- Journal of Chongqing Medical University Issue 4, (1995)
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  CLC： R730.26
- Published：1995，
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[1]邓华瑜,范维珂,李园园.肌源性肿瘤的结蛋白、波型蛋白及肌动蛋白表达特性[J].重庆医科大学学报,1995(04):251-254.

THE EXPRESSION ON DESMIN,VIMENTIN AND ACTIN IN MYOGENIC TUMORS. [J]. Journal of Chongqing Medical University (4).(1995)
[1]邓华瑜,范维珂,李园园.肌源性肿瘤的结蛋白、波型蛋白及肌动蛋白表达特性[J].重庆医科大学学报,1995(04):251-254. DOI：

THE EXPRESSION ON DESMIN,VIMENTIN AND ACTIN IN MYOGENIC TUMORS. [J]. Journal of Chongqing Medical University (4).(1995) DOI：

摘要

采用ＡＢＣ－ＤＡＢ免疫组织化学方法分析３５问各种类型肌源性肿瘤的结蛋白、波型蛋白及肌动蛋白表达特性．结果显示恶性肿瘤细胞表达结蛋白能力下阶，可呈结蛋白表达阴性、波型蛋白阳性，或共同表达结蛋白与波型蛋白，此与恶性肿瘤细胞低分化或未分化密切相关。血管平滑肌瘤的中间丝表达呈现３种不问类型。肌动蛋白（Ａｌｐｈａ－Ｓｒ－１）显示对胚胎型横纹肌肉瘤的良好染色反应。

Abstract

he expression of desmin

vimentin and actin in 35 casses of myogenic tumors ofvarious types was analyzed by immunohistochemical technique

The results show thatthe expression of desmin in malignant myogenic tumor cells is weakened

and some ofthem can be negative for desmin but positive for vimentin or coexpress both of desminand vimentin. It is closely related to poorly-differentiation or undifferentiation ofmalignant tumor cells.The intermediate filament expression in vascular leiomyomasexhibits three different types. Actin(Alpha-Sr-1)reveals stronger staining for em-bryonal rhabdomyosarcoma.

关键词

肌源性肿瘤免疫组织化学结蛋白波型蛋白肌动蛋白

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