The cliniacal application of aprotinin in cardiac valve replacement under cardiopulmonary bypass

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- The cliniacal application of aprotinin in cardiac valve replacement under cardiopulmonary bypass
- Journal of Chongqing Medical University Issue 1, (1997)
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  CLC： R654
- Published：1997，
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[1]周天荣,房秀生,张幼君.抑肽酶在体外循环心脏瓣膜替换术中的临床应用[J].重庆医科大学学报,1997(01):59-61.

The cliniacal application of aprotinin in cardiac valve replacement under cardiopulmonary bypass. [J]. Journal of Chongqing Medical University (1).(1997)
[1]周天荣,房秀生,张幼君.抑肽酶在体外循环心脏瓣膜替换术中的临床应用[J].重庆医科大学学报,1997(01):59-61. DOI：

The cliniacal application of aprotinin in cardiac valve replacement under cardiopulmonary bypass. [J]. Journal of Chongqing Medical University (1).(1997) DOI：

４０例心脏瓣膜替换术病人随机分为对照组（Ｃ组）和抑肽酶组（Ａ组）。于ＣＰＢ前、ＣＰＢ３０ｍｉｎ和ＣＰＢ后１ｈ分别观察血小板计数、血小板聚集率和血小板粘附率、并记录术后２４ｈ胸腔引流量和输血量。结果表明抑肽酶能有效地保护血小板功能，显著地减少术后出血量和输血量。

\ 40 patients undergoing cardiac valve replacement were divided into two groups:C(Control) N=20;A(Aprotinin n =20 who received 3

000

000 KIU each during CPB.The platelet count

the platelet aggregation and abhesion funcition were determined at three-time points and the first 24 hour postoperative chest drainage

blood transfusion were recorded .The results showed:Aprotinin can provide effective protection for platelet function

markedly reduce postopertive chest drainage and blood transfusion.

体外循环抑肽酶血小板功能

Cardiopulmonary bypssAprotininplatelet function

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Related Institution

Department of Cardiothoracic Surgery,the Second College of Clinical Medicine, Chongqing Medical University

重庆医科大学第二临床学院心胸外科

Department of Obstetrics and Gynecology，The First Affiliated Hospital of Chongqing Medical University

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