Effect of hemodialysis on levels of plasma endothelin-1in patients with uremia

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Effect of hemodialysis on levels of plasma endothelin-1in patients with uremia

更新时间：2024-01-17

- Effect of hemodialysis on levels of plasma endothelin-1in patients with uremia
- Journal of Chongqing Medical University Issue 4, (1997)
- 作者机构：
  
  临床学院中医科
- 作者简介：
- 基金信息：
- DOI：
  CLC： R692.5
- Published：1997，
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[1]曹文富,李荣亨,张晓恒,徐天玉.血液透析对尿毒症患者血浆内皮素-1的影响[J].重庆医科大学学报,1997(04):314-315.

Effect of hemodialysis on levels of plasma endothelin-1in patients with uremia. [J]. Journal of Chongqing Medical University (4).(1997)
[1]曹文富,李荣亨,张晓恒,徐天玉.血液透析对尿毒症患者血浆内皮素-1的影响[J].重庆医科大学学报,1997(04):314-315. DOI：

Effect of hemodialysis on levels of plasma endothelin-1in patients with uremia. [J]. Journal of Chongqing Medical University (4).(1997) DOI：

摘要

用ＲＩＡ法测定２４例尿毒症患者血液透析前、后和２０例健康成人血浆内皮素－１（ＥＴ－１）水平。结果：健康成人为２６．７３±７．３７ｐｍｏｌ／Ｌ：尿毒症患者血透前、后分别为９８．４６±１１．８５ｐｍｏｌ／Ｌ和８４．１０±１４．５６ｐｍｏｌ／Ｌ，均高于健康成人的水平（Ｐ＜０．０１）。血透后血浆ＥＴ－１显著低于血透前，但与Ｂｕｎ、Ｓｃｒ、平均动脉压（ＭＡＰ）变化及超滤量之间无显著相关性。

Abstract

The levels of plasma endothelin - 1 (PET- 1) in 24 cases of patients with uremia before and after hemodialysis. and in 20 cases of healthy adulta were measured by radioimmuoassay. The results showed that the level of PET -1 was 26.73 ±7.73 pmol/L in the healthy adults; and 98.46 ±11.85pmol/L and 84.10±14.56 pmol/L before and after hemodialysis correspondently in patients with uremia

both significantly higher than the healthy control(P<0.01). The level of PET - 1 after hamodialysis was obviously lower than before hemodialysis

but no significant correlation with Bun . Scr. MAP and quantity of ultrafiltration liquid was found.

关键词

血浆内皮素－1尿毒症血液透析

Keywords

Plasma Endothelin- 1uremiahemodialysis

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