Effect of intracerebroventricular in jection of ciprofloxacin ondlectric activity,power spectrum and frequency distribution in rats

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Effect of intracerebroventricular in jection of ciprofloxacin ondlectric activity,power spectrum and frequency distribution in rats

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- Effect of intracerebroventricular in jection of ciprofloxacin ondlectric activity,power spectrum and frequency distribution in rats
- Journal of Chongqing Medical University Issue 4, (1997)
- 作者机构：
  
  内江师范专科学校生物系
- 作者简介：
- 基金信息：
- DOI：
  CLC： R-332
- Published：1997，
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[1]杨素珍,陆杰,范维正,黄仲荪,钱元恕.侧脑室注射环丙沙星对大鼠脑电、脑电功率谱及频率分配的影响[J].重庆医科大学学报,1997(04):321-324.

Effect of intracerebroventricular in jection of ciprofloxacin ondlectric activity,power spectrum and frequency distribution in rats. [J]. Journal of Chongqing Medical University (4).(1997)
[1]杨素珍,陆杰,范维正,黄仲荪,钱元恕.侧脑室注射环丙沙星对大鼠脑电、脑电功率谱及频率分配的影响[J].重庆医科大学学报,1997(04):321-324. DOI：

Effect of intracerebroventricular in jection of ciprofloxacin ondlectric activity,power spectrum and frequency distribution in rats. [J]. Journal of Chongqing Medical University (4).(1997) DOI：

摘要

以不同剂量的环丙沙星（３皿ｕｇ·Ｋｇ－１及６００ｕｇｋｇ－１）注入大鼠右侧脑室后，于皮层感觉运动区记录皮层脑电图作脑电功率谱及频率分配分析。注射后两剂量组皮层均先后出现痫样放电（大剂量、小剂量组潜伏期分别为３５．３３±３５．１６和１５３．８８±９４．２１９）脑电功率谱及频率分配分析主要表现为总功率及脑电的快成分（ａ、β和β２）所占百分比增加而功率主峰频段δ波所占百分比减少。提示：环丙沙星对中枢神经系统具有兴奋作用。

Abstract

Electrocorticogram (ECOG) was recorded and analysed in sensorimotor area of rat cortex

by using power spectrum analysis tecchnique

after 300ug . kg-1 and 600ug . kg-1 Ciprofloxacin (CPLX) injected into right ventricle of

brain. The epileptiform discharge appeared at 35

33±35.16 sec and 153.88±94.21 sec in large - dose and small dose - group respectively. The total power and power percentage of . x and band increased

while those of the band with the peak of the main power ( band ) decreased . These results suggest that CPLX can increase excitability of CNS.

关键词

环丙沙星脑电图脑电功率谱频率分配

Keywords

CiprofloxacinECOGPower spectrumFrequency distribution

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