This study discussed the method of terminating 10-16 weeks’ gestation of 78 women using miferpistone andmisoprostol. Method:First

pregnant women with 10￣16 weeks’ gestation well given 150mg miferpistone at onetime or at several times. 48 hours later were given 0.6mg misoprostol. Then according to the labour of uterine

todetermine whether being given 0.4mg misoprostol per 2 hours per 3 hours. But the maximum quantity ofinisoprostol was beyond 1.8mg. Results:The successful rate of abortion was 88.5 % (in which complete abortion was65.2% and incomplete abortion was 34.8%). The failng rate was 11.5%. Aveage time of abortion was 7.3±2.2hours. The amount of vaginal bleeding was less than that of menstruation. Side effects were small. The abortivetime was not significantly different(P>0.05) between parous and nonparous women. Conclusiog: Usingmiferpistone and misoprostol terminating 10￣16 weeks’ bestation has better effects and less side - effects is worthwhile being popularized.