Plasma motilin levels were determined in 38 patient with multiple sustem organ failure (MSOF) and in 42 normal subjects by radioimmunoassay

The results showed that;The plasma motilin levels of MSOF patients in critical stage were significantly higher than those in convalescence stage and those in controls (P<0.01); and the levels in convalescence stage were not significantly different from those in controls (P>0.05); Plasma motilin levels wore increased with more failure organs: Plasma motilin levels were significantly higher in MSOF with failure of central nerve system

gastrointesinal tract and liver

It was also significantly higher in the death group. Plasma levels of motilin in MSOF patients bad a positive correlation with the severity scores of disease. The mechanism of the elevation and clinical significance of plasma motilin levels in patients with MSOF was discussed