A clinical study on amniotic membrane transplantation for treatment of severe ocular surface disorders

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A clinical study on amniotic membrane transplantation for treatment of severe ocular surface disorders

更新时间：2024-01-17

- A clinical study on amniotic membrane transplantation for treatment of severe ocular surface disorders
- Journal of Chongqing Medical University Issue 2, Pages: 166-168(2001)
- 作者机构：
  
  重庆医科大学临床学院眼科,重庆,400016
- 作者简介：
- 基金信息：
- DOI：
  CLC： R779.6
- Published：2001，
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[1]赵敏,李鸿,周善壁,徐智勇,彭俊超.羊膜移植治疗严重眼表面疾病的临床观察[J].重庆医科大学学报,2001(02):166-168.

A clinical study on amniotic membrane transplantation for treatment of severe ocular surface disorders. [J]. Journal of Chongqing Medical University (2):166-168(2001)
[1]赵敏,李鸿,周善壁,徐智勇,彭俊超.羊膜移植治疗严重眼表面疾病的临床观察[J].重庆医科大学学报,2001(02):166-168. DOI：

A clinical study on amniotic membrane transplantation for treatment of severe ocular surface disorders. [J]. Journal of Chongqing Medical University (2):166-168(2001) DOI：

摘要

目的：研究羊膜移植治疗严重眼表面疾病的临床疗效。方法：对严重眼表面疾病29例31眼，其中急性眼烧伤炎症期6眼，陈旧性眼烧伤睑球粘连及其它眼表疾病25眼，施行单纯羊膜移植（15眼）和羊膜移植联合板层角膜移植术（16眼），随访3～18个月，平均8.4个月。结果：急性眼烧伤病变中4眼的炎症显著减轻，角膜未继续溶解，上皮修复；慢性病变中有20只眼的眼表面获得重建，睑球粘连得到治愈或显著改善，视力不同程度提高。结论：对于急性严重的眼烧伤，羊膜移植能有效地阻止炎症和角膜溶解的发展，防止或减轻疤痕；对于陈旧性眼烧伤和其它眼表面疾病，羊膜是一种良好的生物学材料移植后能有效的重建眼表面。

Abstract

Objective: To investigate the effect of amniotic membrane transplantation for severe surface disorders. Methods: Simple amniotic membrane transplantation 15 eyes and combined with lamellar keratoplasty 16 eyes were performed on severe ocular surface disorders ( acute ocular chemical and thermal burns 6 eyes

chronic ocular burn with severe symblepharon and other ocular surface disease 25 eyes). These patients were followed for 3-18 months ( mean 8.4 months). Results: The inflammation was decreased obviously in four out of six acute eye burns

no progressive corneal melting and perforation were seen . Ocular surface reconstruction was successful in 20 of 25 eyes with choronic ocular surface disorders. Symblepharon was cured or decreased. Visual acuity was improved in various degrees. Conclusion: Amniotic membrane transplantation can effectively reduce inflammation and block corneal melting in acute eye burn. As a good biologic material amniotic membrane can be used to reconstruct ocular surface for treating chornic ocular burn with symblepharon and other ocular surface diseases.

关键词

羊膜移植眼表面疾病化学烧伤

Keywords

Amniotic membranetransplantationOcular surface diseaseChemical burns

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重庆市第三人民医院眼科

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