WU Yongzhong, et al. Study of fractionation regimen of radiotherapy in bone pain caused by cancer. [J]. Journal of Chongqing Medical University (2):200-202(2002)
WU Yongzhong, et al. Study of fractionation regimen of radiotherapy in bone pain caused by cancer. [J]. Journal of Chongqing Medical University (2):200-202(2002)DOI:
Study of fractionation regimen of radiotherapy in bone pain caused by cancer
Objective: To explore the ideal fractionated regimen of radiotherapy applied in malignant tumor with bone metastases. Methods: 165 patients with bone metastases were admitted in our department from May 1996 to Dectember 2000 and answered to the inclusive criteria. According to the different radiotherapeutic fractionation regimen
they were divided into three groups: Group I (conventional fractionation)
Group II (large fractionation) and Group III (larger fractionation). Their different efficacy
bone pain score
initial time of effect and relieved degree of bone pain were compared respectively. Results: The total response rate of radiotherapy applied in malignant tumor with bone metastases is 94.5%
the striking response rate is 77.0%
and there is statistical diversity in striking response rate between Group III and Group I (P<0.05); of the three groups
there is statistical difference in terms of the bone pain score before and after radiotherapy (Group I and Group II
P<0.05; Group III P<0.01); comparing Group III with Group I and Group III with Group II
there is striking diversity in the initial time of effect (P<0.01
<0.05
respectively). As far as the initial time of effect
bone pain score and relieved degree of bone pain and so on
the larger fractionation group (Group III) are superior to the other groups. Conclusion: Larger fractionation regimen is the ideal approach of radiotherapy applied in malignant tumor with bone metastases.
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Related Author
Liu Xianfeng
Zhou wei
Wu Yongzhong
Wang Ying
Luo Qian
Cui Zhen
Li Duojie
Li Yan
Related Institution
Department of Radiation Oncology,Chongqing Cancer Institute & Hospital & Cancer Center
Department of Radiotherapy,The First Affiliated Hospital of Bengbu Medical College
Department of Oncology,The First Affiliated Hospital of Chongqing Medical University