Changes of erectile function in diabetic rats and the effect of treatment with insulin

您当前的位置：

首页 >

文章列表页 >

Changes of erectile function in diabetic rats and the effect of treatment with insulin

更新时间：2024-01-17

- Changes of erectile function in diabetic rats and the effect of treatment with insulin
- Journal of Chongqing Medical University Issue 2, Pages: 142-144(2002)
- 作者机构：
  
  重庆医科大学临床学院内分泌科,重庆,400016
- 作者简介：
- 基金信息：
- DOI：
  CLC： R587.2
- Published：2002，
扫描看全文
[1]黎英荣,汪恕萍.糖尿病大鼠阴茎勃起功能的变化及胰岛素的治疗作用[J].重庆医科大学学报,2002(02):142-144.

Changes of erectile function in diabetic rats and the effect of treatment with insulin. [J]. Journal of Chongqing Medical University (2):142-144(2002)
[1]黎英荣,汪恕萍.糖尿病大鼠阴茎勃起功能的变化及胰岛素的治疗作用[J].重庆医科大学学报,2002(02):142-144. DOI：

Changes of erectile function in diabetic rats and the effect of treatment with insulin. [J]. Journal of Chongqing Medical University (2):142-144(2002) DOI：

摘要

目的:探讨糖尿病对大鼠阴茎勃起功能的影响

胰岛素是否能提高糖尿病大鼠阴茎勃起功能。方法:应用雄性SD大鼠腹腔内注射链脲佐菌素（）制造糖尿病动物模型

用胰岛素对糖尿病大鼠进行干预治疗周

再通过观察各组大鼠注STZ8射阿朴吗啡（）后的阴茎勃起情况来评价其勃起功能。APO结果:糖尿病组（组）大鼠阴茎勃起率、阴茎勃起次数较对照D组（组）明显降低（CP）

用胰岛素治疗组（组）上述指标明显高于组（<0.01DMDIDP）

较组低（<0.01CP）

阴茎<0.01勃起功能与HbA1呈显著负相关。C结论:糖尿病严重损害阴茎勃起功能

胰岛素治疗可提高糖尿病大鼠阴茎勃起功能。

Abstract

Objective: To study the changes of erectile function in diabetic rats and whether the function of penile erection was improved by the treatments of insulin. Methods: Male Sprague-Dawley rats were injected intraperitoneally with streptozotozin (STZ) to make experimental models of diabetes mellitus(DM). Diabetic rats were treated with insulin for 8 weeks

then injected with apomorphine in all of the rats

and penile erections were observed in order to evaluate their erectile function. Results: The penile erectile rates and penile erectile times in the DM rats (D group) were decreased significantly (P<0.01) than the controls (C group). And the above indexes in the diabetic rats treated with insulin(DI group) were significantly higher than those in D group ( P<0.01)

but lower than those in C group(P<0.01). Negative correlation was seen between the function of penile erection and HbA1C. Conclusion: The erectile function was seriously impaired in rats with DM

and the function of penile erection in diabetic rats was improved by the treatment of insulin.

关键词

糖尿病阴茎勃起功能障碍胰岛素

Keywords

diabetes mellitusErectile dysfuntioninsulin

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Protection of sodium glucose cotransporter-2 inhibitors on diabetic nephropathy

Research progress of ghrelin and diabetes mellitus

Research progress of a new anti-diabetic agent:SGLT2 inhibitors

Application of metformin in the treatment of type 1 diabetes

Protective effect and mechanism of palmatine on diabetic mouse aorta

Related Author

Hu Yumei

Xia Jiajia

Ren Wei

Liang Huimin

Deng Huacong

Xiong Xin

Long Min

Cai Leiqin

Related Institution

Department of Endocrinology,The First Affiliated Hospital of Chongqing Medical University

Department of Endocrinology,Xinqiao Hospital,Third Military Medical University

Department of Endocrinology,Southwest Hospital of The Third Military Medical University

Central Laboratory,Xinqiao Hospital,Third Military Medical University

Daping Hospital,Third Military Medical University

⁰