The value of immature reticulocyte count in monitoring the suppression of bone marrow function in patients with chest tumor during postoperative chemotherapy

WANG Mei; et al

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The value of immature reticulocyte count in monitoring the suppression of bone marrow function in patients with chest tumor during postoperative chemotherapy

更新时间：2024-01-17

- The value of immature reticulocyte count in monitoring the suppression of bone marrow function in patients with chest tumor during postoperative chemotherapy
- Journal of Chongqing Medical University Issue 4, Pages: 585-586(2006)
- 作者机构：
  
  1. 重庆医科大学附属第一医院检验科
  2. 重庆市防疫站
- 作者简介：
- 基金信息：
- DOI：
  CLC： R730.4;R730.5
- Published：2006，
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[1]王梅,陈爽.网织红细胞计数在监测胸部肿瘤患者化疗后骨髓抑制状态的探讨[J].重庆医科大学学报,2006(04):585-586+596.

WANG Mei, et al. The value of immature reticulocyte count in monitoring the suppression of bone marrow function in patients with chest tumor during postoperative chemotherapy. [J]. Journal of Chongqing Medical University (4):585-586(2006)
[1]王梅,陈爽.网织红细胞计数在监测胸部肿瘤患者化疗后骨髓抑制状态的探讨[J].重庆医科大学学报,2006(04):585-586+596. DOI：

WANG Mei, et al. The value of immature reticulocyte count in monitoring the suppression of bone marrow function in patients with chest tumor during postoperative chemotherapy. [J]. Journal of Chongqing Medical University (4):585-586(2006) DOI：

摘要

目的:探讨网织红细胞计数监测胸部肿瘤患者化疗后骨髓抑制状态的临床价值。方法:41例胸部肿瘤患者（其中肺癌22例

食管癌19例）

根治术后均接受紫杉醇联合顺铂的化疗方案。采用sysmexSE-9000全自动血细胞分析仪动态观察化疗过程中外周血网织红细胞和白细胞数。结果:与化疗前相比

化疗后第7天高荧光强度网织红细胞（HFR）和中荧光强度网织红细胞（MFR）之和（HFR+MFR）显著下降（P<0.01）

而白细胞下降没有显著性意义（P>0.05）。化疗后第14天上两项指标均降低（P<0.01）结论:网织红细胞计数下降较白细胞计数下降早

可作为早期评价肿瘤病人化疗过程中骨髓造血状态的敏感指标。

Abstract

Objective: To investigate the clinical value of immature reticulocyte count in early monitoring the suppression of bone marrow function in patients with chest tumor during postoperative chemotherapy.Methods:Forty-one patients with chest tumor(22 with lung cancer?19 with esophagus cancer) received chemotherapy after radical operation.Several indexes including reticulocyte count and white blood cell(WBC) were detected with sysmex SE-9000 automated analyzer during the procedure of postoperative chemotherapy.Results:Compared with the value before chemotherapy

HFR+MFR was significantly lower than that at 7 days after chemotherapy(P<0.01)

indicating that function of marrow was suppressed.Meanwhile the WBC count kept unchanged.After two weeks

the count of HFR+MFR and WBC reduced significantly.Conclusion:The change of reticulocyte count is earlier than that of WBC

with demonstnates reticulocyte count may act as a sensitive indicator in monitoring the suppression of bone marrow function in patients with chest tumor during chemotherapy.

关键词

网织红细胞骨髓抑制化疗胸部肿瘤

Keywords

Reticulocyte countThe suppression of bone marrow functionchemotherapyChest tumor

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