Clinical significance of a-L-Fucosidase activity in the diagnosisof primary hepatic carcinoma

CHEN Mingfang

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Clinical significance of a-L-Fucosidase activity in the diagnosisof primary hepatic carcinoma

更新时间：2024-01-17

- Clinical significance of a-L-Fucosidase activity in the diagnosisof primary hepatic carcinoma
- Journal of Chongqing Medical University Issue 3, Pages: 440-442(2006)
- 作者机构：
  
  重庆市渝北区人民医院检验科,重庆,401120
- 作者简介：
- 基金信息：
- DOI：
  CLC： R735.7
- Published：2006，
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[1]陈鸣放.a-L-　岩藻糖苷酶对诊断原发性肝癌的临床意义[J].重庆医科大学学报,2006(03):440-442.

CHEN Mingfang. Clinical significance of a-L-Fucosidase activity in the diagnosisof primary hepatic carcinoma. [J]. Journal of Chongqing Medical University (3):440-442(2006)
[1]陈鸣放.a-L-　岩藻糖苷酶对诊断原发性肝癌的临床意义[J].重庆医科大学学报,2006(03):440-442. DOI：

CHEN Mingfang. Clinical significance of a-L-Fucosidase activity in the diagnosisof primary hepatic carcinoma. [J]. Journal of Chongqing Medical University (3):440-442(2006) DOI：

摘要

目的:探讨a-L-岩藻糖苷酶（a-L-Fucosidase

AFU）对诊断原发性肝癌（primaryhepaticcarcinoma

PHC）的临床意义。方法:对80例正常人、33例肝癌患者、37例肝炎患者、42例肝硬化患者、10例转移性肝癌患者和37例其它恶性肿瘤患者所测的血清检测AFU活性值并进行统计后

比较各组AFU水平差异。结果:血清AFU水平

PHC组（41.2±14.1U/L）明显高于正常对照组（20.5±7.2U/L）、转移性肝癌组（22.2±13.6U/L）、其它恶性肿瘤组（22.0±7.1U/L）

P<0.01和肝硬化组（25.5±13.0U/L）（0.01<P<0.05）。结论:a-L-岩藻糖苷酶是PHC的特异性标志物

可用于PHC的早期诊断。

Abstract

Objective: To analyse the clinical significance of a-L-Fucosidase(AFU) in the diagnosis of primary hepatic carcinoma(PHC).Methods: The activity of serum AFU was measured in 33 patients with PHC

42 patients with cirrhosis

37 patients whit hepatitis

10 patients with secondary liver cancer

37 patients with other malignant tumors and 80 normal persons.The differences of the level of AFU between the groups were compared.Results: The mean serum AFU activity was significantly higher in patients with PHC(41.2±14.1 U/L) than that in normal persons(20.5±7.2U/L)

secondary liver cancer(22.2±13.6 U/L)

other kinds of malignant tumors(22.0±7.1 U/L)

P<0.01 and hepatocirrhosis(25.5±13.0 U/L)

0.01<P<0.05.Conclusion:AFU is a specific maker in the PHC and can be used to diagnosis early PHC.

关键词

a-L-岩藻糖苷酶原发性肝癌肿瘤标志物

Keywords

Serum a-L-fucosidasePrimary hepatic carcmomatumor marker

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Related Institution

Department of Oral and Maxillofacial Surgery,The First Affiliated Hospital of Chongqing Medical University

重庆医科大学临床学院普外科

重庆医科大学临床学院普外科博士生

重庆医科大学临床学院普外科重庆医科大学临床学院普外科博士生

Department of Clinical Laboratory, College of Clinical Medicine, Chongqing Medical University

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