Clinical study on the treatment of acute bacterial infection by domestic ceftizoxime sodium

LIU Chuan; et al

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Clinical study on the treatment of acute bacterial infection by domestic ceftizoxime sodium

更新时间：2024-01-17

- Clinical study on the treatment of acute bacterial infection by domestic ceftizoxime sodium
- Journal of Chongqing Medical University Issue 6, Pages: 871-873(2006)
- 作者机构：
  
  1. 重庆医科大学附属第二医院泌尿外科
  2. 重庆医科大学附属第一医院泌尿外科
  3. 重庆医科大学附属第二医院呼吸内科
  4. 重庆医科大学附属第二医院检验科
  5. 重庆医科大学基础医学院病理学教研室
- 作者简介：
- 基金信息：
- DOI：
  CLC： R515
- Published：2006，
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[1]刘川,吴小候,张唯力,周向东,胡自力,黄长武,李昱.国产头孢唑肟钠治疗中重度细菌性感染的临床观察[J].重庆医科大学学报,2006(06):871-873+885.

LIU Chuan, et al. Clinical study on the treatment of acute bacterial infection by domestic ceftizoxime sodium. [J]. Journal of Chongqing Medical University (6):871-873(2006)
[1]刘川,吴小候,张唯力,周向东,胡自力,黄长武,李昱.国产头孢唑肟钠治疗中重度细菌性感染的临床观察[J].重庆医科大学学报,2006(06):871-873+885. DOI：

LIU Chuan, et al. Clinical study on the treatment of acute bacterial infection by domestic ceftizoxime sodium. [J]. Journal of Chongqing Medical University (6):871-873(2006) DOI：

摘要

目的:以进口头孢唑肟钠作对照

评价国产头孢唑肟钠治疗敏感菌引起的中重度感染的有效性和安全性。方法:采用随机、双盲、平行对照研究。两组用药方法相同:静脉滴注

每日2次

每次2.0g

疗程:7～14天。然后分别观察临床疗效、细菌学疗效及不良事件。结果:纳入疗效分析的合格病例共50例

其中试验组25例

对照组25例。试验组痊愈率为64.00%

总有效率为96.00%;对照组痊愈率为76.00%

总有效率为100%。试验组和对照组对细菌的清除率分别为89.47%和100%。两组均未发生不良事件。结论:国产头孢唑肟钠治疗中重度细菌性感染与进口头孢唑肟钠同样安全有效。

Abstract

Objective:To evaluate the efficacy and safety of domestic ceftizoxime sodium on the treatment of acute bacterial infection compared with the imported one.Methods:A randomized

comparative

double blinded trial was conducted.The usage of the two medicines was the same: The dose was 2.0g

bid and the duration of treatment was 7~14 days.The clinical efficacy

bacterial eradication and adverse reaction were observed.Results:The total number of final evaluated subjects was 50 with 25 subjects in domestic ceftizoxime sodium group and 25 subjects in imported ceftizoxime sodium group(control group).Clinical efficacy rate and bacterial eradication rate for domestic ceftizoxime sodium were 96.00% and 89.47%

respectively.Clinical efficacy rate and bacterial eradication rate for imported ceftizoxime sodium were 100% and 100%.No adverse reaction was observed in two groups.Conclusion:Domestic ceftizoxime sodium has the same efficacy and safety as the imported one on the treatment of acute bacterial infection.

关键词

头孢唑肟钠细菌感染安全性有效性

Keywords

CeftizoximeBacterial infectionsafetyefficacy

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