Comparison of postoperative patient-controlled intravenous analgesia effects between lornoxicam and tramadol on patients undergoing of oral maxillofacial surgery

LUO Yulin; et al

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Comparison of postoperative patient-controlled intravenous analgesia effects between lornoxicam and tramadol on patients undergoing of oral maxillofacial surgery

更新时间：2024-01-17

- Comparison of postoperative patient-controlled intravenous analgesia effects between lornoxicam and tramadol on patients undergoing of oral maxillofacial surgery
- Journal of Chongqing Medical University Issue 2, Pages: 266-267(2006)
- 作者机构：
  
  1. 重庆医科大学附属口腔医院麻醉科
  2. 重庆医科大学附属口腔医院麻醉科,重庆,400015
- 作者简介：
- 基金信息：
- DOI：
  CLC： R782.054
- Published：2006，
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[1]罗玉琳,郁葱.氯诺昔康和曲马多用于颌面部术后病人静脉自控镇痛的比较[J].重庆医科大学学报,2006(02):266-267+274.

LUO Yulin, et al. Comparison of postoperative patient-controlled intravenous analgesia effects between lornoxicam and tramadol on patients undergoing of oral maxillofacial surgery. [J]. Journal of Chongqing Medical University (2):266-267(2006)
[1]罗玉琳,郁葱.氯诺昔康和曲马多用于颌面部术后病人静脉自控镇痛的比较[J].重庆医科大学学报,2006(02):266-267+274. DOI：

LUO Yulin, et al. Comparison of postoperative patient-controlled intravenous analgesia effects between lornoxicam and tramadol on patients undergoing of oral maxillofacial surgery. [J]. Journal of Chongqing Medical University (2):266-267(2006) DOI：

摘要

目的:比较氯诺昔康和曲马多对颌面部手术病人术后镇痛作用及不良反应。方法:40例颌面部手术病人随机分为两组

Ⅰ组（n=20）氯诺昔康组

Ⅱ组（n=20）曲马多组

均采用澳美电子镇痛泵PCA

其内设置和控制的参数有:（1）持续剂量:2ml/h;（2）锁定时间:20min;（3）PCA剂量:1ml。分别于术后12h、24h、36h、48h随访观察镇痛效果（VAS法）、镇静程度（Ramsay评分）、按压次数以及呼吸抑制、恶心呕吐、头昏等副作用。结果:两组病人VAS评分分别为2.1±1.6和2.5±1.7（P>0.05）

镇痛效果差异无显著性意义。氯诺昔康组术后恶心例数为2例

曲马多为8例（P<0.01）;呕吐例数分别为1例和4例。结论:氯诺昔康和曲马多均可于颌面部病人术后镇痛

而氯诺昔康镇痛效果更好

不良反应轻

是颌面部手术患者较为理想的术后镇痛模式。

Abstract

Objective: To compare the analgesic efficiency and adverse drug reactions of patient-controlled intravenous analgesia(PCIA) with Lornoxicam and Tramadol in patients undergoing the operation in cranio-cervical region.Methods: Forty ASAⅠ～Ⅱadult patients

who undergoing the operation in cranio-cervical region were randomly divided into two groups

both of which were diluted into 100ml with sodium and background 2ml/h

lockout time 15min

PCA bolus 0.5ml.The efficiency of analgesia provided by PCA was assessed by:(1)visual analogue scale(VAS) at 12

36h

48h after the operation;(2)adverse drug reactions such as nausea and vomiting

dizziness

respiratory depression and so on.Results: There was no statistically significant difference between the two groups in VAS score(P>0.05)

There were 2 cases of nausea and one case of vomit in Lornoxicam group

as compared with 8 cases of nausea and 4 cases of vomit in Tramadol group.The number of nausea is 2 vs 8(P<0.01)

voimiting 1 vs 4 in the two groups.Conclusion: Both lornoxicam and tramadol can be used in postoperative analgesia for patients undergoing oral maxillofacial surgery

of which lornoxicam has a better analgesia effect with less side effect and is a preferable choice.When used in patient-controlled intravenous analgesia

Lornoxicam has a safe and effect.condition

It can decrease the occurrence of side-effect each other when used with tramadol

especially nausea and vomit.

关键词

氯诺昔康曲马多自控镇痛

Keywords

LornoxicamPatient controlled intravenous analgesiaOral maxillofacial operation.

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Related Author

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Related Institution

Department of Anesthesioly,the First Affiliated Hospital,Chongqing Medical University

重庆医科大学附属第一医院麻醉科

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