The study about pretransplantation MELD score in predicting short-term survival of patients with end-stage liver disease post liver transplantation

ZHANG Longqun; et al

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The study about pretransplantation MELD score in predicting short-term survival of patients with end-stage liver disease post liver transplantation

更新时间：2024-01-17

- The study about pretransplantation MELD score in predicting short-term survival of patients with end-stage liver disease post liver transplantation
- Journal of Chongqing Medical University Issue 1, Pages: 94-97(2007)
- 作者机构：
  
  1. 重庆医科大学附属第一医院肝胆外科
  2. 重庆医科大学附属第一医院肝胆外科,重庆,400016
- 作者简介：
- 基金信息：
- DOI：
  CLC： R657.3
- Published：2007，
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[1]张隆群,黄平,王济明.MELD评分预测终末期肝病肝移植术后短期生存率的研究[J].重庆医科大学学报,2007(01):94-97.

ZHANG Longqun, et al. The study about pretransplantation MELD score in predicting short-term survival of patients with end-stage liver disease post liver transplantation. [J]. Journal of Chongqing Medical University (1):94-97(2007)
[1]张隆群,黄平,王济明.MELD评分预测终末期肝病肝移植术后短期生存率的研究[J].重庆医科大学学报,2007(01):94-97. DOI：

ZHANG Longqun, et al. The study about pretransplantation MELD score in predicting short-term survival of patients with end-stage liver disease post liver transplantation. [J]. Journal of Chongqing Medical University (1):94-97(2007) DOI：

摘要

目的:探讨MELD评分对终末期肝病肝移植术后短期生存率的预测效果。方法:回顾性分析我院自2000年1月￣2005年11月33例行肝移植手术的终末期肝病受者术前MELD评分及术后3个月、6个月的生存率

依据MELD评分结果将受者分为3组（≤20

21￣30之间

≥30）

分析比较各组生存率之间有无统计学差异。同时比较他们术中的尿量。结果:术后3个月总的生存率为90.1%（30/33）

6个月的生存率为81.8%（27/33）

MELD分值≤20的受者与分值在20￣30之间患者的3个月生存率分别为100.0%和92.3%（P=0.861）

两组比较差异无显著性。MELD分值≥30的受者术后3个月生存率与前两组比较差异均有显著性（P值分别为0.012和0.041）。术后存活时间大于3个月的受者术中尿量为126.2±118.9m1/h

术后3个月内死亡的受者为25.3±22.6ml/h

两者差异有显著性（P=0.0001）。结论:1.终末期肝病肝移植术前MELD评分不能完全预测术后的生存率

因为两者不存在线性关系

只有在达到一临界点的时候

生存率才出现明显下降;2.术中尿量可以综合评价术前、术中各种因素对肾功能的损害程度以及术后肾功能状况

而且与术后生存率密切相关。

Abstract

Objective:The aim of this study is to explore pretransplantation MELD score in predicting shortterm survival of patients with endstage liver disease post liver transplantation.Methods:We studied 3 months and 6 months patient survival in 33adult patients who underwent liver transplantation between January 2000 and November 2005 in our hospital.The MELD score pretransplantation was recorded.We shared categories of their MELD score(≤20

21~30

≥30)and compared their survival.In our study

we also compared urine volume(ml/h)of the patients during operation.Results:The total survival rates in 3 month and 6 months after transplantation were respectively 90.1%(30/33)、81.8%(27/33)

there were respec-tively100.0%、92.3%(P =0.861)in those patients with a MELD score of lower 20 and 21~30 in 3 monbhs swwival rate

they had no significance.We found only those patients with a MELD score of 30 or higher had a survival that was markedly lower than the rest(P =0.012 and 0.041)in 3 months survival rocte.The urine volume(ml/h)of survival patients whese survival time exceeded 3 months during operation(126.2±118.9m1/h)was obviously higher than the dead ones within 3 months(25.3±22.6ml/h)

they were significant(P =0.0001).Conclusions:1 The ability of the pretransplantation MELD score to predict short-term survival of patients with end-stage liver disease post liver transplantation is uncomplerely

because they do not have linear relation and there is a threshold in the MELD score beyond which survival decreases in such a fashion.2 The urine volume(ml/h)during operation can predict the lesion of Kidney from the factors before and during operation.It also correlates to the risk of patients post-transplantation.

关键词

肝移植终末期肝病生存率MELD评分

Keywords

liver transplantationEnd-stage liver diseasesurvival rateMELD score

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