Experimental study on lipid regulation function of the Xi-zhi-jiang Capsule

PU Xiaodong; et al

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Experimental study on lipid regulation function of the Xi-zhi-jiang Capsule

更新时间：2024-01-17

- Experimental study on lipid regulation function of the Xi-zhi-jiang Capsule
- Journal of Chongqing Medical University Issue 2, Pages: 176-177(2007)
- 作者机构：
  
  1. 重庆医科大学中医药学院经典理论教研室
  2. 重庆医科大学中医药学院经典理论教研室,重庆,400050
- 作者简介：
- 基金信息：
- DOI：
  CLC： R151
- Published：2007，
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[1]蒲晓东,尹涛.喜之降胶囊调脂作用的实验研究[J].重庆医科大学学报,2007(02):176-177+188.

PU Xiaodong, et al. Experimental study on lipid regulation function of the Xi-zhi-jiang Capsule. [J]. Journal of Chongqing Medical University (2):176-177(2007)
[1]蒲晓东,尹涛.喜之降胶囊调脂作用的实验研究[J].重庆医科大学学报,2007(02):176-177+188. DOI：

PU Xiaodong, et al. Experimental study on lipid regulation function of the Xi-zhi-jiang Capsule. [J]. Journal of Chongqing Medical University (2):176-177(2007) DOI：

摘要

目的:为研究喜之降胶囊调节血脂的效果

观察了喜之降胶囊对高脂血症（HL）大鼠血清脂质和肝脏脂水平的影响。方法:实验根据大鼠体重、血脂水平进行随机分组

设正常对照组、高脂饲料对照组、喜之降胶囊低、中、高剂量组（分别为0.28、0.55、1.10g/（kg.bw））。受试物每天经口灌胃给予。4周末测定血清胆固醇（TC）、甘油三酯（TG）、高密度脂蛋白胆固醇（HDL-C）

同时测定肝脏TC、TG。结果:喜之降胶囊各组与高脂饲料对照组比较

大鼠血清TC、TG水平降低

差异有显著性（P<0.05）

喜之降胶囊对高脂大鼠肝脏胆固醇、甘油三酯有显著的降低作用（P<0.01）。结论:喜之降胶囊有降低高脂大鼠血脂水平的作用。

Abstract

Objective:To observe the effect of the Xi-zhi-jiang Capsule on serum and liver lipid levels of rats with hyperlipidemia to study the effects of Xi-zhi-jiang capsule on blood Lipid regulation.Methods:Male SD rats were randomly divided into five groups(normal control group

high lipid fed group and three Xi-zhi-jiang capsule groups

which were administrated Xi-zhi-jiang capsule of 0.28

0.55

1.10(g/(kg.bw))respectively.Four weeks later

bodyweight

the serum TC

HDL-C and the liver TC and TG were measured.Result: The rat’s serum TC and TG in Xi-zhi-jiang capsule treatment groups was lower than those of high lipid fed groups

and the difference was significant(P<0.05);the Xi-zhi-jiang capsule could remarkably lower the liver to the TC and TG of HL rat(P<0.01).Conclusion:The Xi-zhi-jiang capsule could lower serum and liver lipid of rats with hyperlipidemia.

关键词

高脂血症大鼠喜之降胶囊

Keywords

hyperlipidemiaratsThe Xi-zhi-jiang Capsule

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