Pathogens and their drug resistance in senile patients with lower respiratory tract infection

TONG Yonghong; et al

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Pathogens and their drug resistance in senile patients with lower respiratory tract infection

更新时间：2024-01-17

- Pathogens and their drug resistance in senile patients with lower respiratory tract infection
- Journal of Chongqing Medical University Issue 9, Pages: 974-976(2007)
- 作者机构：
  
  1. 重庆市肿瘤医院内科
  2. 重庆市肿瘤医院检验科
- 作者简介：
- 基金信息：
- DOI：
  CLC： R56
- Published：2007，
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[1]童永红,甘晓协.老年下呼吸道感染患者痰中细菌学分布及耐药性分析[J].重庆医科大学学报,2007(09):974-976.

TONG Yonghong, et al. Pathogens and their drug resistance in senile patients with lower respiratory tract infection. [J]. Journal of Chongqing Medical University (9):974-976(2007)
[1]童永红,甘晓协.老年下呼吸道感染患者痰中细菌学分布及耐药性分析[J].重庆医科大学学报,2007(09):974-976. DOI：

TONG Yonghong, et al. Pathogens and their drug resistance in senile patients with lower respiratory tract infection. [J]. Journal of Chongqing Medical University (9):974-976(2007) DOI：

摘要

目的:研究老年下呼吸道感染患者痰中细菌学分布及耐药情况

指导临床用药。方法:采用常规痰细菌培养检出病原菌

用单纸片扩散法检测药敏

以双纸片法检测超广谱β-内酰胺酶（ESBLs）。结果:共分离出致病菌263株

其中

革兰氏阴性（G-）杆菌108株

占38.7%

肺炎克雷伯氏菌30株、大肠埃希氏菌26株、阴沟肠杆菌21株、不动杆菌17株;革兰氏阳性（G+）球菌64株

占24.3%

金黄色葡萄球菌28株、表皮葡萄球菌19株;真菌91株

占34.6%。在肺炎克雷伯菌和大肠埃希氏菌中

产ESBLs19株

总阳性率为33.9%。大多数G-杆菌对亚胺培南保持较高敏感性。结论:老年患者下呼吸道感染以G-杆菌为主

致

Abstract

Objective:To investigate the distribution of common pathogens of senile lower respiratory tract infection and drug resistance.to improve clinical therapeutic efficacy.Methods: The susceptibility to antimicrobial agents was tested with diffusion method on mueller-Hinton medium.The double-dish test for ESBLs Confirmed all putative ESBLs-producing strains.Results:A total of 263 strains were obtained from lower respiratory tract in senile patients.108 of 263 strains were Gram-negative bacilli(38.7%).There were 30 strains of Klebsiellae pneumonia

26 strains of Escherichia coli

21 strains of E.cloacae and 17 strains of Acinetobacter;64 strains of gram-positive bacteria(24.3%) and 91 strains of fungi(34.6%).Nineteen strains(33.9%) produced ESBLs in Escherichia coli and Klebsiella pneumoniae.Most gram-negative bacilli kept high susceptibility to the imipenem.Conclusions:Grau-negative bacilli were predominant in aged patients with lower respiratory tract infection.Attention should be paid to multi-drug resistance of pathogenic bacteria and fungus infection.

关键词

下呼吸道感染耐药性超广谱β-内酰胺酶

Keywords

Lower respiatory tract infectioudrug resistanceExtended-spectrum β-lactamases(ESBLs).

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