Objective:To analyze the clinical characteristics of enterococcal infection in leukemia patients. Methods:The clinical characteristics of 11 cases of leukemia with enterococcal infection were summarized by contrast to those of 62 cases of non-leukemia patients with enterococcal infection. The statistical analysis of measurement data applied chi square text. Results: In leukemia group

11 cases (100%) used broad-spectrum antibiotic before enterococcal infection

the length of stay of 8 cases (72.2%) exceeded 15 days before enterococcal infection

9 cases (81.2%) were caused digestive tract infections by enterococci

the clinical manifestations of 10 cases (90.9%) were hyperpyrexia after enterococcal infection

and 9 cases (81.2%) had to use Vancomycin to eliminate enterococci. Whereas in non-leukemia group

there were 22 cases (35.5%)

6 cases(9.7%)

14 cases (22.6%)

9 cases (14.5%) and 9 cases (14.5%) respectively in five aspects above mentioned. The differences between two groups were significant (P<0.01

P<0.01

P<0.01

P<0.01 and P<0.01 respectively). In two groups

the resistant rates of enterococci to six usual antibiotics were high

but they were well susceptible to Vancomycin. There was no statistical difference between two groups (P>0.05). Conclusion:Contrast to non-leukemia patients infected by enterococci

leukemia patients were more easily infected by enterococci because to the long-term of using broad spectrum antibiotic

the long length of stay before enterococcal infection and the weakened power of resistances after chemotherapy. Enterococcal infections were mainly hospital infections

and digestive tract infections were most common. The main clinical manifestations were hyperpyrexia and diarrhea. Enterococci were highly resistant to usual antibiotics but well sensitive to Vancomycin.