Objective:To observe the efficacy and safety of Naloxone in treating acute alcoholism. Methods:95 cases of acute alcoholism were randomly divided into the experimental group(n=50) and the control group(n=45).Patients in the experimental group were treated with Naloxone
and patients in the other group were treated with conventianonal therapy
including fluid replacement plus diuretic agent.The time of regaining consciousness in each group were noted. Results:The time of regaining consciousness was shorter in the Naloxone treatment group than that in control group
obviously(P<0.01). And no abverse event occurred. Conclusion:Naloxone could be widely used in treating acute alcoholism