Comparative study of two types of anastomosis to institute vein graft model

CHEN Hao; et al

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Comparative study of two types of anastomosis to institute vein graft model

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- Comparative study of two types of anastomosis to institute vein graft model
- Journal of Chongqing Medical University Issue 8, Pages: 994-996(2008)
- 作者机构：
  
  1. 重庆医科大学附属第一医院胸心外科
  2. 重庆市中山医院心脏外科重庆市心血管疾病治疗研究中心
- 作者简介：
- 基金信息：
- DOI：
  CLC： R-332
- Published：2008，
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[1]陈灏,杨双强,杨庆军.两种吻合方法建立静脉桥狭窄动物模型的比较研究[J].重庆医科大学学报,2008(08):994-996.

CHEN Hao, et al. Comparative study of two types of anastomosis to institute vein graft model. [J]. Journal of Chongqing Medical University (8):994-996(2008)
[1]陈灏,杨双强,杨庆军.两种吻合方法建立静脉桥狭窄动物模型的比较研究[J].重庆医科大学学报,2008(08):994-996. DOI：

CHEN Hao, et al. Comparative study of two types of anastomosis to institute vein graft model. [J]. Journal of Chongqing Medical University (8):994-996(2008) DOI：

摘要

目的:比较两种吻合方法建立静脉桥狭窄动物模型的差别。方法:2.0～2.5kg普通新西兰大白兔17只

分A、B两组

取颈外静脉与颈总动脉进行端端吻合

吻合时分别采用间断吻合（A组）和间断加连续吻合（B组）的方法。术后1月取下静脉桥

采用计算机图像处理系统分析新内膜、中膜厚度。结果:A组手术时间和吻合时间均较B组长

出血多

具有统计学意义;1月后两组静脉桥管壁均增厚

光镜下见新内膜形成

中膜增厚

两组差异没有显著性。结论:间断加连续端端吻合兔颈外静脉-颈总动脉

建立静脉桥模型要优于单纯间断吻合方法。

Abstract

Objective:To compare two type of anastomosis to institute vein graft model.Methods:Studies were performed by using normal New Zealand’s white rabbits(n=17

weight 2.0～2.5kg) which be divided into two group.Every rabbit’s unilateral jugular vein was anastomosed end-to-end with common carotid artery by interrupted suture(group A

n=9)or interrupted and continuous suture(group B

n=8).Samples of tissues were harvested after 1 mouth and examined under a light microscope.The vessel wall dimensions were measured by computer-aided planimentry.Results:The time of anastomosis and whole operation of group A are longer than group B(P<0.05).The bleeding of group A is more than Group B(P<0.05).All vien grafts are unobstructed and the total wall thickening.The neointimal and medial demostracted hyperplasia.But there is not statistically difference between the two goups.Conclusion:The method of anastomosis by interrupted and continuous suture is successfully and excelled that by single interrupted suture.

关键词

动物模型吻合方法兔静脉桥再狭窄

Keywords

animal modelMethod of anastomosisrabbitVein graftrestenosis

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